13,000 x Scale-up of 3-Acetylcoumarin - Demonstration of Scalable Flow Synthesis from R&D to Production without Parameter Re-optimisation

6 June 2012

Dr. Charlotte Wiles | 2012-06-06


Dr. Charlotte Wiles

Starting her research in the area of continuous flow synthesis in 2000, Dr Charlotte obtained her PhD in 2003 entitled ‘Microreactors in organic synthesis’. This was followed by 5 years of Post Doctoral research into the rapidly developing field of continuous flow synthesis, specifically in the area of heterogeneous catalysis for small molecule synthesis. 

In 2008, Dr Charlotte Wiles joined Chemtrix BV as a Senior Chemist where she worked on the commercialisation of lab-scale micro reactor apparatus. In 2010 she was promoted to Chief Technology Officer within Chemtrix BV and in 2013 to CEO, where she continues to research and develop continuous flow systems and solutions for industrial partners; with more recent developments focusing on industrial flow reactors, suited towards the development of flexible tonne-scale production plants, in cooperation with 3M and DSM. 

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