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WHITE PAPER: CONTINUOUS MANUFACTURING - PRODUCING MORE WITH LESS

With the advent of commercially available flow equipment, the technique of continuous processing is now widely accessible for the synthetic chemist facilitating development of not only lab-scale transformations but, as the field matures, also pilot and plant based processes. That said, a challenge for continuous flow technology is that it competes with established, and in most cases fully written off, production infrastructure. It therefore stands to reason that initially uptake has been stronger where safety concerns have prevented the use of existing equipment, capacity increases were required or production is being implemented in territories without existing batch capacity.

 

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FDA Supports the use of Continuous Manufacturing
International Symposium on Continuous Manufacturing of Pharmaceuticals

FDA Supports the use of Continuous ManufacturingOrganised by CMAC (Centre for Innovative Manufacturing in Continuous Manufacturing & Crystallisation, UK) & MIT (Massachusetts Institute of Technology, USA) on the request of the FDA, the International Symposium of Continuous Manufacturing of Pharmaceuticals (http://iscmp.mit.edu/) was a 2 day event held in Boston (20-21st May 2014). Attended by industry leaders and technology providers, the Symposium was the ideal platform through which to discuss the potential...

Chemtrix' KiloFlow® featured on cover of Chemical and Engineering news (C&EN)
End to End Chemistry A. Thayer | Chemical & Engineering News, 2014, 92(21), 13

Chemtrix' KiloFlow® featured on cover of Chemical and Engineering news (C&EN)Interesting article on the Flow Chemistry market in this months 'Chemical and Engineering News' After a slow start, pharmaceutical and fine chemicals manufacturers are scaling up continuous processes for production. Please click here for the complete article.

Hydrodynamic characterization of gas-liquid-liquid slug flow and parallel-slug flow through a glass microfluidic chip
Jun Yue, Evgeny V. Rebrov, Jaap C. Schouten

Hydrodynamic characterization of gas-liquid-liquid slug flow and parallel-slug flow through a glass microfluidic chipGas-liquid-liquid flow in microfluidic and microreactor systems has important applications in the production of double emulsions, intensification of liquid-liquid extraction by gas agitation, kinetic studies in organic synthesis via aqueous catalysis in three-phase mode (e.g., hydrogenation, hydroformylation, oxidation). The currently inadequate understanding on the fundamental transport rules of gas-liquid-liquid mixtures in microchannels renders the system design far from...

Symposium 'Waste not want not, profit from sustainable chemistry' at Chemspec Europe 2014
June 18 - 19, Budapest, Hungary

Symposium 'Waste not want not, profit from sustainable chemistry' at Chemspec Europe 2014This two day international RSC Symposium organised in association with Chemistry Innovation and the Green Chemistry Network will be held on the Exhibition Floor at the 2014 Chemspec Europe and Chemsource Exhibitions organised by Quartz Business Media. It will address the challenges facing small scale businesses in minimising waste and operating at a profit using sustainable chemistry. Innovative developments in this field will be highlighted. Our CEO, Dr. Charlotte Wiles...